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However, women who are pregnant or breastfeeding should avoid it, in addition to people with hyperthyroidism ( Furthermore, this herb may interact with sedatives, immunosuppressants, and anticonvulsants, as well as medications for the following conditions ( diabetes high blood pressure psychoactive disorders hypothyroidism Whats more, ashwagandha may stimulate your immune system, potentially exacerbating autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, and lupus

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doi: 10.1016/0041-008x(88)90040-3

For someone weighing 220 pounds at baseline, that is the difference between losing 35 pounds and losing 47 pounds