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Both routes show comparable efficacy in animals, though injections may act faster for localized issues

Helminths residing in the human gut induce tolerogenic DCs, alternatively activated macrophages, and Treg cells, which produce suppressor cytokines that help keep inflammatory T cells and their effector molecules in check (Loukas et al., 2016)

The entire analysis was performed using pyEMMA 66 freely available at github ( Reporting summary Further information on research design is available in the Nature Portfolio Reporting Summary linked to this article

For use in vitamin B12 deficiency associated with cobalt deficiency in cattle and sheep and for vitamin B12 deficiency associated with inadequate vitamin B12 intake or intestinal malbsorption in swine and horses.