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The long-term outlook remains uncertain

Meanwhile, adoption of existing medications for SUD is very low, particularly for AUD: AUD is a leading cause of mortality and morbidity, but compared with other chronic diseases such as cancers, hypertension, diabetes and depression, there is a very small number of US Food and Drug administration (FDA)-approved medications for AUD (acamprosate, disulfiram and naltrexone)

Thyroid medications are goldilocks hormones they need to be used in just the right dose and there are risk factors of being overmedicated

Tolerability depends on the medication, dose, escalation schedule, individual biology, and how consistently you follow provider instructions