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Tennessee's Division of TennCare publishes its preferred drug list quarterly, and prescribers should consult the current edition before initiating therapy

Because swallowing food triggers GLP-1 release from the gut, which dramatically amplifies the insulin response

Excess androgens worsen PCOS symptoms like irregular periods and hirsutism (hair growth on the face, chest, and back)

Despite convincing data suggesting the central role of GLP-1R signalling in the food intake reduction effects of OXM, there were still some unexplained effects of the gut hormone including increased energy expenditure, suggesting a GLP-1R independent mechanism of action (35)