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Under normal physiological conditions, Keap1, as the substrate adaptor of the E3 ubiquitin ligase complex, maintains intracellular redox balance by promoting the ubiquitination and degradation of Nrf2

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The following section mainly introduces the signaling pathways induced by PRRs, including toll-like receptors (TLRs), nucleotide-binding leucine-rich repeat receptors (NLRs), retinoic acid-inducible gene I (RIG-I) -like receptors (RLRs), cytoplasmic DNA sensors (CDSs), and receptors for advanced glycation end products (RAGEs) in relation to ARDS

Li Y, Wang X, Sun Z (2020) Ecotoxicological effects of petroleum-contaminated soil on the earthworm Eisenia fetida