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Common Side Effects Nausea (typically improves after 2-4 weeks) Diarrhea or constipation Decreased appetite (this is the goal) Mild stomach discomfort Fatigue during dose increases When to Call Your Doctor Severe or persistent nausea/vomiting Signs of pancreatitis (severe abdominal pain) Vision changes Rapid heartbeat Signs of allergic reaction Is Semaglutide Right for You

Evidence indicates that GLP-1RAs can reduce the occurrence of MI [70]

This timeline comes directly from the seven-day half-life, following the general pharmacological rule that steady state is achieved after 4 to 5 half-lives

According to the FDA, you should use an FDA-cleared sharps disposal container