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PSM with age, sex, race, and disease comorbidities was then conducted, yielding 162,253 matched patients for analysis

Tirzepatide is a dual GIP and GLP-1 receptor agonist, which gives it a slightly different mechanism of action than semaglutide's single-target approach

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8 Based on data from the MAESTRO-NASH trial, resmetirom demonstrated histological benefits with a number needed to treat of five for the resolution of MASH and 8.5 for fibrosis regression, 9 thus posing significant economic challenges