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PMID: 31330811

The same review also notes that vitamin C works alongside other antioxidants in the skin, particularly glutathione, as part of an interconnected defense system that helps regenerate and recycle these compounds so they can keep neutralizing free radicals rather than becoming exhausted after a single use

(2019) Inhibition of amyloid-induced toxicity by ergothioneine in a transgenic Caenorhabditis elegans model

Therefore, some dysregulated metabolites, particularly those involved in amino acid, lipid, and acylcarnitine metabolism, may reflect a combination of disease-related metabolic disturbances and therapeutic interventions