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Description

Non-competitive overactivation of IGF-1R signaling (through mutations) support NSCLC resistance to xentuzumab (BI 836845), a monoclonal antibody targeting both IGF-1 and IGF-2 (72)

doi: 10.7759/cureus.2658

GLP-1 medications do not selectively target belly fat but produce generalized fat loss throughout the body, including significant reductions in abdominal and visceral fat

Ethics statement The animal study was reviewed and approved by New Jersey Medical School-Rutgers