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In December the TGA added this indication under the heading Reduction in risk of major adverse cardiovascular events: Wegovy is indicated as an adjunct to standard of care therapy to reduce the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction or non-fatal stroke) in adults with established cardiovascular disease, with a Body Mass Index (BMI) 27kg/m2, and without established Type 1 or Type 2 diabetes. The decision to approve the Wegovy-branded semaglutide product was based on the SELECT study published in late 2023 a large international trial, backed by maker Novo Nordisk, involving around 18,000 non-diabetic patients with a BMI of at least 27

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