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Retatrutide is a novel investigational peptide developed by Eli Lilly that targets three key receptors: GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon receptors

Recent years have seen a number of new drugs become available for the management of type 2 diabetes, and emerging evidence suggests that many of these agents have benefits beyond their effects on blood glucose control

Under these circumstances, it has been shown that astroglia releases TNF-, followed by a release of glutamate while also activating microglia [48]

Insulin is a hormone that helps sugar move from the blood into the cells, where it can be used for energy