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These polymers have the ability to change from the liquid state to the gel state at temperatures close to body temperature, therefore allowing useful formulations that are applied to the targeted auris structure(s)
Furthermore, these cohorts represented populations with relatively mild disease severity proxies, indicated by low rates of prior advanced therapy use
The biologically active L-stereoisomer contrasts with the inactive D-carnitine and potentially toxic DL-racemic mixture
J Inherit Metab Dis 24:359366 Artuch R, Colome C, Sierra C, Brandi N, Lambruschini N, Campistol J, Ugarte D, Vilaseca MA (2004) A longitudinal study of antioxidant status in phenylketonuric patients
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