Sufficient amounts of free carnitine can facilitate the entry of accumulated acyl-CoA into mitochondria, reducing its inhibition of adenine nucleotide translocase, thereby allowing oxidative phosphorylation to proceed smoothly
Furthermore, Redox proteomics studies found that many antioxidant enzymes that are allocated in the mitochondria, including glutathione-S-transferase Mu, peroxiredoxin 6, GSH and ATP synthase are oxidized in AD, which might compromise their functions by increasing oxidative stress conditions that prevail in AD affected brain regions (Swomley and Allan Butterfield, 2015)
These are legitimate clinical questions - and they should be directed to the prescribing clinician, not answered by marketing materials or content articles
Therefore, more research is needed for a better understanding of folate bioavailability from food and influencing factors 1,37,75,98,120,146,147,149,184,185,186,187,188,189,190,191,192,193,194,195,196,197,198,199,200,201,202,203,204,205,206,207,208,209,210,211,212,213,214,215,216,217,218,219,220,221,222,223,224,225,226,227,228,229,230,231,232,233,234,235,236,237,238,239,240,241,242,243,244,245,246,247