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Regarding gastrointestinal tolerability, 83% of treated participants reported no or only mild key gastrointestinal adverse events

In addition, the ultrasmall nanotrap can capture endogenous iron and target it for transport to the TAMs inside the tumor, and iron was released from the nanotrap when exposed to lysosomal acidity and intracellular H 2 O 2 and generate oxidative stress thereby reprograming the TAMs to activated M1 TAMs and inducing immune response and ultimately inhibiting tumor growth (34)

As science continues to evolve, staying informed and alert remains the best way to keep patients safe and well