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Both conditions are driven by excessive Vascular Endothelial Growth Factor (VEGF) activity

Stress: Both physical and emotional stress increase the production of free radicals, which in turn consumes your antioxidant reserves

Dietary modifications: Eat smaller, more frequent meals rather than large portions Avoid high-fat, greasy, or heavily spiced foods, particularly during dose escalation Reduce alcohol intake, which can independently irritate the gastrointestinal tract Stay well hydrated, especially if experiencing loose stools Lifestyle adjustments: Avoid lying down immediately after eating Allow adequate time between meals to support gastric emptying Medication timing: Some individuals find that choosing an injection day when dietary intake can be more easily managed helps reduce the impact of acute gastrointestinal symptoms

We might expect that even broader variety of resistance mechanisms would be revealed were it to be used in clinical settings