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Patients on both medications should monitor blood pressure readings regularly, especially during the first 46 weeks of semaglutide initiation when dose escalation occurs

From baseline to week 104, numerically larger proportions of participants in the semaglutide treatment group than in the placebo group achieved a weight loss of 5% (74.7% vs

Lee & Kim, 2022) Side Effects: dry mouth blurred vision & enlarged pupil causes presynaptic inhibition of norepinephrine release, which can affect autonomic control of the lens & pupil

One proof-of-concept clinical trial in patients with obesity and type 2 diabetes