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The chemistry of peptide degradation Hydrolysis represents the primary degradation mechanism for peptides exposed to moisture at elevated temperatures

One potential cost advantage: oral medications eliminate the expenses associated with injection supplies (needles, syringes, sharps containers, alcohol swabs) that add up over months and years of treatment

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Phase II trials showed a good safety profile but didnt demonstrate weight-loss efficacy meaningfully better than placebo, which is why Metabolic Pharmaceuticals didnt pursue further regulatory approval