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Elements crucial for ROS control, cell protection, and known antiviral responses include the glutathione cycle, especially the levels of GSH and GSSG forms, along with glutathione-associated enzymes such as glutathione transferases (GSTs), glutathione reductases (GRs), and glutathione peroxidases (GPXs).The involvement of glutathione or glutathione treatment in resistance reactions to plant viruses has been reported for various virus types, including potato virus Y-PVY (Otulak-Kozie et al., 2022a) on different cultivar of potato, tobacco mosaic virus TMV on tobacco (Zhu et al., 2021), turnip mosaic virus-TuMV (2023) on Arabidopsis and obuda pepper virus - pepper interaction (Zechmann et al., 2005

In addition to Nrf2, activation of PPAR- and the AMPK pathway can also facilitate the GSH system

Many people supplement with ALCAR, because of its potential benefits