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Circulation 132 , e121e122 (2015)

For example, GLP-1 RAs have been shown to help in heart failure and also to have beneficial effects on heart rhythm.[ref] Cognitive function: Studies are showing positive effects on cognitive function and possibly reduced (or delayed) dementia with GLP-1s

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There are two distinct forces at play here that are putting pressure on payers: On the one hand are rare diseases like Hemophilia B, for which we now have curative treatments with price tags in the millions