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3xTg males fed a DL diet had significantly decreased survival (log-rank test, p = 0.009) relative to AL-fed males (Fig

In some ways, the failure of the first generation of PPAR agonists paved the way for the Ozempic revolution

Increased hippocampal neurogenesis influences anxiety and depressive behavior through the HPA axis and is considered a promising strategy to promote antidepressant-like effects (Hill et al., 2015)

Matrix degradation depends upon the balance between MMPs, TIMPs and converting enzymes (MT1-MMP and stromelysin) (Li and Friedman, 1999)