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H., Kwak, H

It encodes a 185 kDa transmembrane glycoprotein with intrinsic tyrosine kinase activity and is a member of the epidermal growth factor receptor (EGFR) family (59) HER2/neu plays critical roles in cellular development, proliferation, and differentiation in tissues where it is expressed

We will not address this question further in this paper, as peer reviewed papers on that topic are lacking

Frequently, brain tumor and its therapy are endocrinologically devastating for children, and the most common residua are growth failure or short stature, which may be caused by the high rate of GHD in children after cranial radiation and radiation effects on skeletal growth after spinal or whole-body radiation treatment (Schriock et al., 1991)