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A 0.4 per cent GTN ointment is licensed for use in chronic anal fissures

Dies sollte bei der Behandlung von Patienten mit eingeschrnkter Nierenfunktion bercksichtigt werden, da belkeit, Erbrechen und Durchfall zu Dehydrierung fhren knnen, die eine Verschlechterung der Nierenfunktion verursachen kann

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