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The common symptoms include: constant hunger excessive thirst fatigue frequent urination blurry vision numbness in hands or feet Type 2 diabetes differs from type 1 diabetes, which is an autoimmune condition in which insulin-producing cells in the pancreas stop producing the hormone

In a 2025 report on the lidERA breast cancer trial, giredestrant reduced any recurrence by 30% and distant or metastatic recurrence by 31% versus tamoxifen or an aromatase inhibitor, with 92.4% recurrence-free survival at three years compared with 89.6% for standard hormonal therapy, according to Breastcancer.org's report on the lidERA trial

Other side effects of Zepbound include kidney and gallbladder disease, hypoglycemia, pancreatitis, allergic reactions, injection site reactions, and suicidal thoughts

Objective measurements like skinfold thickness and subjective assessments of skin elasticity (the pinch test on the back of the hand or abdomen) can also help track progress