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Patients considering GLP-1 discontinuation should work closely with their healthcare team to develop individualized maintenance plans, establish realistic expectations about weight trajectory, and implement close monitoring for weight regain

Ideally incorporate rigorous baseline and follow-up assessments: DEXA, body composition, visceral fat, renal function, endocrine panels, inflammatory biomarkers (IL-6, TNF-, SASP markers if available)

Therefore, we may recommend this therapy to patients undergoing rigorous physical activities, those recovering from injuries, and individuals who may have compromised immune systems or gut health issues

Some provincial formularies provide coverage with restrictions