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[1] [2] Administered as a once-weekly subcutaneous injection, semaglutide works by enhancing glucose-dependent insulin secretion, suppressing glucagon release, and slowing gastric emptying

TRIUMPH-1 is the flagship obesity trial, targeting adults with a body mass index (BMI) of 30 or greater, or a BMI of 27 or greater with at least one weight-related comorbidity such as hypertension, dyslipidemia, or obstructive sleep apnea

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