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The former mechanism is preferred because RS scavengers can be consumed during the reaction and may generate toxic radicals derived from the chelators (Halliwell and Gutteridge, 2015)

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Tesamorelin has a stabilized molecular structure that gives it a longer functional duration and more consistent effects than Sermorelins short 10 to 12 minute half-life

Cross-Trial: The Only Fair Comparisons This is the honesty centerpiece of the comparison, and it can be stated in one sentence: no published randomized controlled trial has ever directly compared tesamorelin against sermorelin