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Without offering a citation for a published paper or sharing any data, Sikirics 2025 review states that this clinical trial found that the drug was safe and well-tolerated in humans

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Quick Reference: Protocol Community-reported AHK-Cu use centers on a topical serum applied to the scalp (for hair interest) or skin (for the copper-peptide skin properties extrapolated from GHK-Cu)

[1] [2] However, longstanding neurological complications, such as peripheral neuropathy or cognitive changes, may require three to six months of consistent treatment before significant improvement occurs, and some damage may be irreversible if treatment is delayed