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oleic acid, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA)] demonstrate beneficial actions in NAFLD by inhibiting oxidative stress and inflammation and reducing lipid deposition [30]

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[85] reported that phosphorylated STAT3 selectively interacted with SMAD3 protein, thus blocking the formation of transactivating SMAD3/SMAD4 complex in cultured human liver cells and keratinocytes

These changes were linked with measurable extension of telomere length in both normal and cancer cell models, suggesting that Epithalon may affect cellular mechanisms involved in maintaining chromosome end stability under experimental conditions