Based on the STEP 1 clinical study, the semaglutide-treated group reported weight loss beginning with the first assessment after randomization at week 4, reaching its lowest reported weight loss at week 60.[2,4] STEP 1 included 1961 patients randomly assigned to treatment with semaglutide or placebo combined with diet and exercise.[4] Dosage Forms And Strengths Semaglutide is currently available as a clear and colorless injectable solution.[2] The injections come in five different pre-filled, disposable, and single-dose pens[2]: 0.25 mg/0.5 mL 0.5 mg/0.5 mL 1 mg/0.5 mL 1.7 mg/0.5 mL 2.4 mg/0.5 mL Safety Common side effects of semaglutide are gastrointestinal-related.[2,5] These are nausea, vomiting, and diarrhea
The best way, of course, to lose weight is to eat healthy and exercise
Moreover, the study does not provide details of minor side effects or any potential risks associated with long-term use [6]
If mandatory, one unresolved question is whether plan sponsors will retain flexibility to use formulary placement and rebate negotiations to prefer certain products