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The key variable was adherence to the same time each week, which allowed the body's metabolic rhythm to synchronize with the medication's presence, creating predictable periods of enhanced fullness signals

Raw data on effect of Ex-4 on the protein expression in BLA of heroin withdrawal mice

These preclinical results were supported by genome-wide association studies, which have identified variants with reduced activity at the human GIP receptor locus that are associated with reduced BMI [72]

[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Lubrano V., Pingitore A., Traghella I., Storti S., Parri S., Berti S., Ndreu R., Andrenelli A., Palmieri C., Iervasi G., et al