Among the 60 participants treated with GSBR-1290, only one (2.8%, from the T2DM group) discontinued the study due to drug-related adverse events (AEs)
Common side effects may include: Nausea: Especially after meals or following a dose increase Vomiting: Triggered by persistent or severe nausea Constipation: Due to slower digestion and reduced food intake Diarrhea: Including loose stools or changes in bowel habits Bloating: Caused by delayed stomach emptying Abdominal discomfort: Such as mild cramping, pressure, or digestive upset Tips to manage GLP-1 side effects Reduce portion sizes Many patients find that eating smaller meals helps reduce nausea and digestive discomfort
But theres a massive difference between supporting GLP-1 and actually delivering the hormone itself
[DOI] [PMC free article] [PubMed] [Google Scholar] 69.Davies M., Faerch L., Jeppesen O.K., Pakseresht A., Pedersen S.D., Perreault L., Rosenstock J., Shimomura I., Viljoen A., Wadden T.A., et al