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Alternatives to tirzepatide Since Mounjaro is used for managing type 2 diabetes, any medication that helps reduce blood sugar could be a possible alternative, including: Other GLP-1 receptor agonists like semaglutide (Ozempic), liraglutide (Victoza), and dulaglutide (Trulicity) DPP-4 inhibitors like linagliptin (Tradjenta) and sitagliptin (Januvia) SGLT2 inhibitors like empagliflozin (Jardiance) and dapagliflozin (Farxiga) Sulfonylureas like glimepiride (Amaryl) and glyburide (Diabeta) TZDs like rosiglitazone (Avandia) and pioglitazone (Actos) If you are looking for an alternative weight-loss medication to Zepbound, your options include: GLP-1 receptor agonists like liraglutide (Saxenda) and semaglutide (Wegovy) Orlistat (Xenical, Alli) Naltrexone-bupropion (Contrave) Phentermine (Adipex, Suprenza) Phentermine-topiramate (Qsymia) When considering alternatives, talk with your healthcare provider, so you can go over the pros and cons of each medication to find the one thats right for you

Journal of Translational Medicine, 21(1), 36