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Before diving in, understand: Most evidence is from rodent studies effects in humans may differ No established safe dose range in humans doses are extrapolated from animal work Long-term effects unknown synaptogenesis is powerful

Clinical data have demonstrated VK0214 is well tolerated and reduces plasma levels of very long-chain fatty acids, supporting its potential to address the underlying biology of disease and improve patient outcomes over time.

Publications on heart failure (HF) with preserved ejection fraction (HFpEF) date back to 198485

Table 2 Application and therapeutic effect of multiple probiotics in different animal models