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Therefore, melasma can categorize as a photoaging disorder especially in patients with genetic vulnerability (Passeron and Picardo, 2018)
90 Interestingly, the antirheumatic drug leflunomide also clearly protected mice from AIH by suppressing the JNK-mediated activation of mitochondrial permeabilization
With the lung infiltration of neutrophils and macrophages triggered by CS, proinflammatory cytokines such as interleukin -1(IL-1) and tumor necrosis factor- (TNF-) induce a cascade of amplification effects of inflammation, and activate nuclear factor- B (NF- B) (Di Stefano et al., 2002)
Fatty acid synthase (FAS) is a marker of increased risk of recurrence in lung carcinoma
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