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(2012, European Journal of Clinical Pharmacology) showed that after two weeks of berberine at 300mg three times daily, CYP2D6 activity dropped substantially (dextromethorphan metabolic ratio increased nine-fold), and midazolam concentrations rose 38 to 40% due to CYP3A4 inhibition

Interested in science from a young age, most of Bloom's career has been focused on gut hormones

Neuroprotection from injury cascades After a neurological injury such as stroke, TBI, or the chronic damage seen in neurodegeneration a cascade of secondary injury events unfolds: excitotoxicity, uncontrolled apoptosis, oxidative stress, and neuroinflammation

Progress in Biophysics and Molecular Biology , 107(2), 248-256