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Synergistic effects have also been observed when curcumin is combined with other bioactive compounds-naringenin, genistein and epigallocatechin gallate (Ghobadi and Asoodeh, 2023)

Release 338 , 119136 (2021)

Unlike the previous concept, that melanomas develop de novo intra-orally, it can be hypothesized that melanomas are preceded by oral melanotic macules or melano-acanthoma, having melanocytic hyperplasia and/or dysplasia instead of having the same number of typical melanocytes with an increased tendency to synthesize melanin pigment