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Even though several studies show an association between the levels of lipid oxidation products and disease progression, experimental evidence suggests that compounds such as reactive aldehydes and cholesterol oxidation products are characteristic features of hepatic oxidative damage [11]

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55 In this analysis utility values were applied exclusively to body weight reduction, rather than to different stages of liver disease progression, further reinforcing the conservative nature of the approach

But this rarely translates to a significant difference in patient outcomes