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Christensen MB, Lund AB, Jrgensen NR, Holst JJ, Vilsbll T, Knop FK (2020) Glucose-dependent insulinotropic polypeptide (GIP) reduces bone resorption in patients with type 2 diabetes
It has a high affinity for copper ions (Cu), forming a stable and biologically active complex that may support coppers bioavailability and intracellular activity
The most commonly reported effect is slight water retention, which reflects the supplement's effectiveness in helping muscles maintain optimal hydration levels
These findings suggest that while FOXO4 is involved in the senescence pathway, it also plays a role in maintaining the viability of senescent Leydig cells by suppressing their apoptotic response, which could contribute to the accumulation of senescent cells [1]
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