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Recent studies further indicate that pomegranate can attenuate aggressive cancer phenotypes by reducing breast cancer cell invasion and motility (366, 368) diminishing cancer-associated inflammation (369)and suppressing cellular proliferation, effects that are likely linked to its antioxidant capacity (370)

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Studies have shown that testosterone deficiency exacerbates metabolic disorders, leading to reductions in lactate, acetyl-CoA, and tricarboxylic acid cycle (TCA cycle) products, hindering fatty acid -oxidation, and affecting collagen synthesis and creatine formation [237]