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(2024) demonstrated that nitazoxanide and tizoxanide activates AMPK, inhibits STAT3 and Smad2/3 activation, collagen I expression and secretion leading to inhibition of liver fibrosis induced by carbon tetrachloride-induced and bile duct ligation in mice (Liu et al., 2024)

Data Extraction Extracted variables included study design, peptide agent and formulation, dosing regimen and route of administration when reported, musculoskeletal indication, comparator group, outcome measures, efficacy findings, and adverse events

Frontiers in physiology, 8, 390

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