is trizepitide a glp-1 Tirzepatide caused roughly half as many patients to stop treatment because of gastrointestinal side effects as semaglutide. In the first major head-to-head obesity trial, GI side effects caused treatment discontinuation in: Tirzepatide Retatrutide vs Semaglutide and Tirzepatide:

Individual circumstances : Does the patient have specific nutritional deficiencies or health conditions that might warrant supplementation

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