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In this case, miRNAs can alter the gene expression of the CPT2 and CPT1 genes, which in turn affect mitochondrial function and fatty acid oxidation.[ref] Similarly, supplemental L-carnitine can affect inflammatory pathways through altering the expression of microRNAs that in turn decrease inflammatory cytokines.[ref] Genotype report: Carnitine Access this content: An active subscription is required to access this content

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whereas, the ubiquitin-proteasome system (UPS) and autophagy-lysosomal pathways are activated, accelerating muscle protein degradation [15]