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However, transplantation of MPO -/- macrophages into Ldlr -/- mice, also markedly increased atherosclerosis, and this was confirmed in MPO -/- / Ldlr -/- double knockout mice compared to MPO +/+ / Ldlr -/- controls (289)

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Reduced MT-1 activity may impair the bodys ability to eliminate heavy metals, thereby increasing fetal exposure