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Ryzyko Hipoglikemii : W przypadku pacjentw z cukrzyc stosujcych rwnie inne leki obniajce poziom glukozy, terapie GLP-1 i GIP mog zwiksza ryzyko hipoglikemii (niskiego poziomu cukru we krwi), co wymaga cisego monitorowania i potencjalnej korekty dawkowania

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For example, increased INS promoter methylation levels and INS mRNA suppression were observed under over-nutrition conditions and obese T2DM patients