Using conserved transcription factor (TF) binding motifs, higher-order promoter regulatory structures identified potential cooperating TFs that explained the cell type enrichment pattern
Note also that GSH inhibits both GCL and GS, so it is not clear by inspection of the diagram what the effect of raising the activities of GCL and GPX will be

Common Sources of EDCs: Plastics (especially water bottles, food containers, and plastic wraplook for BPA, phthalates) Conventional cleaning products with harsh chemicals Synthetic fragrances found in air fresheners, candles, laundry detergents, and skincare Pesticide-treated produce and non-organic animal products How to Reduce Your Exposure: Choose non-toxic personal care and cleaning products labeled fragrance-free or EWG-verified Ditch plastic : Use glass, stainless steel, or silicone containers for food and drinks Go organic : Prioritize organic produce (especially the Dirty Dozen) and hormone-free animal products Filter your water : Use a high-quality filter for drinking and bathing water to remove heavy metals, chlorine, and EDCs Improve indoor air quality : Ventilate your home and consider an air purifier to reduce airborne chemicals and allergens Every small change reduces the burden on your hormonesand your skin

Weight management research explores compounds that influence energy balance, fat storage, and metabolic regulation