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However, the patients enrolled in EMPA-REG had little CKD at the start of the trial

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Lingvay I, Catarig AM, Frias JP, et al

If hiccups persist despite firstline self-care and begin to interfere with eating, sleeping, or blood sugar control, a clinician may consider prescribing short courses of drugs such as metoclopramide, baclofen, gabapentin, or chlorpromazine under supervision, with attention to side effects and interactions