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Available dosage forms: tablets, suspension, intravenous (limited use) Aldactone is most commonly available in oral tablet form, though liquid suspension preparations are also used, particularly for pediatric or elderly patients

87 In liver cancer, DNMT1 induces hypermethylation and silencing of BEX1 , a negative regulator of the Wnt/-catenin signaling pathway, thereby enhancing CSC maintenance, promoting tumor growth, and contributing to therapy resistance

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