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The mechanisms by which methimazole and/or PTU cause hepatotoxicity are not clarified completely yet, but it seems that these mechanisms might be different between currently available antithyroid drugs.29 Furthermore, the risk factors that render patients more susceptible to antithyroid drugs-induced hepatic injury are not fully recognized
doi: 10.3390/nu16070994 42
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Astrocytes in AD model animals demonstrated up-regulated expression of genes (CPS1, OCT, ASL, ARG1, and ODC1) and metabolites (aspartate, ammonia, urea, putrescine, and GABA) of the urea cycle
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