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Raspini et al., 2021)

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MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks (vol 123, pg 1213, 2005)

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Other symptoms of IC: Fatigue, depression, anxiety, difficulty sleeping, and changes in bowel habits 2

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SGLT2 = sodium-glucose co-transporter 2

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