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In short, despite some heterogeneity across the trials, GLP-1 receptor agonists were shown to reduce the hazard ratios [95%CI] for 3-MACE by 12 [618]%, cardiovascular death by 12 [419]%, myocardial infarction by 9 [016]% and stroke by 16 {724]%

For me though, I dont want to take something that speeds up my metabolic rate when I dont need to speed up my metabolic rate

For patients with cardiometabolic risk profiles that include elevated blood glucose, insulin resistance, or cardiovascular risk, complementary agents including Metformin and the SGLT2 Protocol address overlapping but distinct mechanisms